The missiles managed to destroy a command center, a communications hub, an ammunition depot and an unspecified number of ISIS fighters.
Russian Federation has been helping Damascus in the fight against terrorists since September 30, 2015, at President Bashar Assad's request.
Advanced stealth technology is coupled with 18 torpedoes and eight cruise missiles, which Russian Federation claims will allow the craft to strike land, sea and air targets.
On September 5, Syrian army troops and allied forces broke the three-year siege on Deir ez-Zor.
Since then, battles have been raging in the city - 60 percent of which has been seized - to rid it off the remnants of the militants.
Philippine government forces have been trying to remove IS-linked militants from the city since May.
Syrian President Bashar al-Assad in a recent message to Iran's Supreme Leader Ayatollah Seyyed Ali Khamenei has thanked the country for its role in lifting the siege of Deir ez-Zor city, an Islamic State stronghold in eastern Syria, IRNA reports.
American-backed Syrian Democratic Forces are also fighting near the city, advancing from the north bank of the Euphrates river, while Assad's forces move in from the south.
Colonel Ryan Dillon, the spokesperson for the US-led coalition, criticized the deal between Syria, Hezbollah, and IS.
A convoy of Islamic State militants and their relatives being evacuated from the border with Lebanon has crossed into an extremist stronghold in eastern Syria, a Syrian monitoring group said Thursday, ending a standoff with the USA -led coalition.
The relocation came in exchange for ISIS-held prisoners and the remains of Lebanese soldiers captured in 2014. On Thursday, a captive Hezbollah fighter was released.
The head of Britain's Syrian Observatory for Human Rights said buses and vehicles carrying about 400 militants and civilians crossed into Deir el-Zour province Wednesday.
The convoy had been stuck in the desert following airstrikes by the U.S-led coalition to prevent its advance.
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