McCain's decision will certainly influence the debate, but it may not block Haspel's confirmation.
"I realize that there are strong disagreements on the effectiveness of the CIA's detention and interrogation program", Haspel wrote in answers to more than 100 questions submitted by committee members and released at her hearing. I know that those who used enhanced interrogation methods and those who approved them wanted to protect Americans from harm.
He remarked: "When I voted to declassify the committee's report on the program in 2014, I wrote about my serious concerns regarding the destruction of videotapes documenting interrogation sessions and said that those involved in the decision to destroy those records against the clear direction of senior USA officials should no longer be leading the agency".
McCain, who was tortured and held captive for five-and-a-half years during the Vietnam War, claimed Haspel's "refusal to acknowledge torture's immorality is disqualifying".
Haspel faced grilling Wednesday by the Senate Intelligence Committee about her role overseeing some CIA operations after the September 11 attacks.
Former CIA Officer Bryan Dean Wright: "Haspel has had a long, successful career battling America's traditional enemies - most especially the Russians - along with newer threats like ISIS and other organizations engaging in radical Islamic terrorism".
She says, "we don't have interrogators and we don't have interrogation expertise". While her family has deep roots there, she grew up as an Air Force brat, following her father to postings all over the world. They said Haspel also agreed that harsh interrogation tactics produced valuable intelligence.
Democratic Senator Martin Heinrich asked her, 'Doesn't that feel like a cover-up?' "Senators should block this nomination".
The CIA investigated too.
Published accounts by former officials and others involved in the CIA's detention programme indicate that Ms Haspel may not only have been directly involved in running a Central Intelligence Agency "black site" in 2002, but may also have "run" the Central Intelligence Agency interrogation programme more broadly for a period, and may also have been involved in covering up possible evidence of crimes under worldwide law.
It's been well-documented that Donald Trump and Republican Arizona Sen.
McCain called Haspel a "patriot" in his statement in Wednesday but referenced her record and testimony before the Senate Intelligence Committee to implore the Senate to vote down her nomination. Joe Manchin, D-W.Va., also announced his support Wednesday.
Haspel's opponents outside Congress include Amnesty International and Human Rights Watch.
The CIA director position opened up after Mike Pompeo was named secretary of state.
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